When I first started really riding lots of miles 4 or 5 years ago, I used to get a bit of a sore bum. The last 2 seasons have been the highest mileage-wise, but no real problems. Even so, I decided to buy a Brooks saddle (B17), and have done about 30 miles on it so far.
My initial thoughts are good. The 'load' seems to be spread over a wider area, thereby reducing pressure 'hot spots'.
My only gripe is I tend to slide forwards a bit, but am putting that down to 'newness'. I have moved the seat forward a few mm on the rail, so time will tell.
I did tilt it back one notch on the seat post, but that instantly put pressure (that I did NOT enjoy) on my gentleman's selection, so I tilted it forwards again.